In human HCC, VE-Cadherin expression correlated inversely with the expression of hypoxia marker CAIX and positively with levels of intratumoral CD3, CD4, CD8, FOXP3 (regulatory T cells [Tregs]), CD68 (macrophages) and myeloperoxidase (neutrophils) (Table 1). This evidence concerns the gene FOXP3 and hepatocellular carcinoma.