When analyzing the individual trial phases, we first of all found that HMECs incubated with uremic serum from patients in the MCO/HF/HF-regimen, starting with MCO dialyzer, had similar KLF2 expression upon incubation MCO serum (end of the first 4-weeks cycle) than upon incubation with HSP, which indicates a beneficial effect of the MCO dialyzer (Figure 6A). The gene discussed is KLF2; the disease is hydrops fetalis.