Some HLA alleles have been demonstrated to be strongly associated with drug-induced SCARs and have been proposed as valid genetic markers for the prediction of drug-induced SCARs such as HLA-B*15:02 for carbamazepine-induced SJS/TEN (Chung et al., 2004; Hung et al., 2006; Tassaneeyakul et al., 2010; Nakkam et al., 2022a), HLA-B*58:01 for allopurinol-induced SCARs (Hung et al., 2005; Tassaneeyakul et al., 2009; Saksit et al., 2017b), or HLA-B*57:01 for abacavir hypersensitivity (Mallal et al., 2002; Mallal et al., 2008). The gene discussed is HLA-B; the disease is Schwartz-Jampel syndrome.