Also, in the study on the effect of peel extract of pomegranate on the animal model of EAE and type 1 diabetes, improvement of the symptoms of the disease obtained, and these changes were caused by the inhibition of the filtration of immune cells into the pancreatic islet cells and the reduction of the production of IL-17 and IFNγ (61). The gene discussed is IFNG; the disease is type 1 diabetes mellitus.