CDH1 and gastric cancer: CDH1 (E‐cadherin) and its related signalling pathways play important physiological roles in maintaining cell adhesion, structure, motility and cell homeostasis55; CDH1 mutation is also associated with GC; and both dysregulation and mutation of the CDH1 gene can increase the proliferation, invasion and/or metastasis of GC cells and promote the occurrence and development of GC.56, 57