Among the top 20 KEGG pathways from KEGG pathway enrichment results, signalling pathways related to GC development included pathways in cancer, viral infection, lipid and atherosclerosis, endocrine resistance, apoptosis, platinum drug resistance, p53 signalling pathway, other cancer‐related pathways, etc. KEGG Mapper was used to draw KEGG maps of the distribution of key targets in the p53 signalling pathway and PI3K‐Akt signalling pathway, as shown in Figure 9. Here, TP53 is linked to cancer.