According to the ROC curves of the core candidate targets, we generated, as shown in Figure 6, the results showed that among the 14 core candidate targets, except for PPARG, the AUC values of TP53, JUN, CASP3, HSP90AA1, VEGFA, HRAS, CDH1, MAPK3, CDKN1A, SRC, CYCS, BCL2L1 and CDK4 were all at (0.5, 1) range, indicating that these 13 key targets are closely related to GC. This evidence concerns the gene CDKN1A and gastric cancer.