The GO analysis of the DEGs revealed that they were involved in a series of cellular processes, lymphocyte chemotaxis, lymphocyte migration, response to interferon-gamma, etc. KEGG analysis illustrated that critical pathways associated with T cell function, such as Graft-versus-host disease, Th17 cell differentiation and JAK-STAT signaling pathway, were upregulated after coculturing with AA-Exos. Here, IFNG is linked to glycogen storage disease VI.