TP53 and infection: The frequency of the DEL/DEL genotype of rs17880560 (TP53) was also higher among those with mono-infection of P. vivax compared to those with mixed infection (P = 0.029; OR = 0.667; 95% CI 0.211–1.669) (Additional file 5: Table S3), indicating that carriers of this genotype may present some level of protection against infections by multiple species of Plasmodium. No marker showed an association in the comparison between mono-infected with P. falciparum and mixed infection (Additional file 6: Table S4).