IFNG and malaria: In human malaria, cellular immune response involves the secretion of high levels of pro-inflammatory cytokines, such as tumour necrosis factor (TNF) [6], interferon-gamma (IFN-γ) [7, 8], the release of free radicals such as reactive oxygen species (ROS) [9], and reactive nitrogen species (RNS) [7, 10], in addition to the production of the anti-inflammatory interleukin-10 (IL-10) to prevent excessive inflammation [6, 8].