INS and malaria: Within malaria subgroups, the INS/INS genotype of rs10562972 (FAS) was significantly more frequent among those infected with P. vivax than those with P. falciparum (P = 0.036; OR = 2.493; 95% CI 1.104–4.551) (Additional file 4: Table S2), suggesting that the carriers of this genotype have a 2.5-fold increased risk of developing malaria from P. vivax infection.