This resistance may be due to plasmids carrying resistance genes such as qacA/B, smr, qacG, qacH, and qacJ. CoNS strains are exposed to selective pressure in the hospital setting, leading to their persistence and the potential to cause infections while also transferring their resistance genes to other pathogens, including S. aureus [9, 14, 22]. Here, LYPD4 is linked to infection.