The proportion of BCR with IgG was greater in the patients from the NMOSD group than in those from the other disease groups (vs. MOGAD, p = 0.001; vs. DSN, p = 0.011); Among the subclasses of IgG, the proportions of IgG1 and IgG2 were higher in the NMOSD compared to the MOGAD group (p = 0.002 and p = 0.078, respectively) (Additional file 1: Fig. S1). Here, BCR is linked to Charcot-Marie-Tooth disease type 3.