GPT and chronic hepatitis B virus infection: Recently, the fibrosis-5 (FIB-5) [14] index using albumin, alkaline phosphatase (ALP), aspartate aminotransferase(AST)/alanine aminotransferase (ALT) ratio, and PLT count has been shown to be superior to the FIB-4 index in predicting severe cirrhosis in patients with chronic hepatitis B and C [15, 16].