We observed significant increases in the expression of proinflammatory cytokines and chemokines such as Ifng, Tnf, Il15, Il18, Cxcl9, Cxcl10, Cxcl12 and Ccl5 in AC484-treated tumours (Extended Data Fig. 5c and Supplementary Table 6). Here, IFNG is linked to neoplasm.