The utility of routine biochemical biomarkers such as hsCRP or antibodies have been investigated for distinguishing several genetic etiologies (HNF1A, HNF4A, HNF1B) from Type 1 or Type 2 diabetes, or for distinguishing HNF1A specifically from Type 2 diabetes using HDL-cholesterol or hsCRP64–69. This evidence concerns the gene HNF1A and type 2 diabetes mellitus.