Selection by age of diabetes diagnosis between 6 and 12 months was supported by a yield of 6% to 28% by level 2 evidence from six studies, although these were limited by only testing for INS or KCNJ11 and ABCC8. Selection by age of diabetes diagnosis beyond 12 months for monogenic diabetes testing was not supported by three studies examining those diagnosed with diabetes up to 24 months. The gene discussed is INS; the disease is diabetes mellitus.