Tu et al (2019) have described the role of YAP1 as an oncogene and as a major driver of squamous subtype pancreatic ductal adenocarcinoma. In this study, they have shown that WNT5A overexpression leads to the activation of YAP1 (Rosenbluh et al, 2012). The gene discussed is WNT5A; the disease is pancreatic ductal adenocarcinoma.