PHOSPHO1 and type 2 diabetes mellitus: Nonetheless, we also observed results that contradict our hypothesis and the observational evidence with disease risk: methylation levels reflecting higher diet quality at cg02650017 (PHOSPHO1) were associated with higher T2D risk, and methylation levels reflecting lower diet quality at cg27395200 (BRD2) were associated with lower CHD risk and at cg23761815 (SLC29A3) were associated with lower SBP and lower T2D risk.