Furthermore, MR analysis supported causal effects of five CpGs [cg02079413 (SNORA54), cg02107842 (MAST4), cg05399785 (WDR8), cg23761815 (SLC29A3), and cg00711496 (PRMT1)] on BMI, of cg00711496 (PRMT1) on T2D, of two CpGs [cg00711496 (PRMT1) and cg05575921 (AHRR)] on CHD, and of cg05399785 (WDR8) on SBP. The gene discussed is PRMT1; the disease is type 2 diabetes mellitus.