Measuring IL6 (cut-off points = 128,53 pg/ml; 92,3% sensitivity and 92,1% specificity), CA-125 (cut-off points = 13249,50 U/ml; 88,5% sensitivity and 89,5% specificity), and HE4 (cut-off points = 410,40 pmol/L; 96,2% sensitivity and 97,4% specificity) levels is useful for clinician to predict tumor resectability in the preoperative patients with advanced epithelial ovarian cancer. The gene discussed is IL6; the disease is ovarian carcinoma.