A recent study revealed that FGFR1 on macrophages are activated by glioma cell-derived FGF20, which inhibits β-catenin degradation through phosphorylating glycogen synthase kinase 3β (GSK3β) and subsequently suppresses macrophage polarization to the M1 phonotypes in vitro (150). This evidence concerns the gene FGFR1 and glioma.