Thus, in the analysis of the Mayo RNA-Seq dataset for Alzheimer’s disease, four of the DV genes detected in the control vs. AD comparison that have the largest estimated SD ratio above 1 are LTBP2, SLPI, C2orf40, and SLC47A1 (Fig. 8). The gene discussed is SLC47A1; the disease is early-onset autosomal dominant Alzheimer disease.