REN and COVID-19: Finally, the potential mechanisms of virus-induced endocrine complications of COVID-19, including direct viral injury, endothelial dysfunction in the highly vascular structures of endocrine glands, cytokine-induced injury, or dysregulation of the renin-angiotensin-aldosterone system (RAAS), might be accompanied by side-effects of the drugs used in COVID-19 management (steroids and antiviral agents) (1, 10, 11).