Finally, because of the availability of potential therapeutic intervention, we also performed cell-cell communication analysis of the CD47-SIRPα pathway which predicted overall decreased signaling after vaccination (Fig. 3E), despite increased CD47 expression on at least one lymphoid (B-cell cluster 2) and one plasmacytoid (B-cell cluster 10) LPL tumor subpopulation. Here, SIRPA is linked to neoplasm.