Despite increased expression of CD47 (“do not eat me” signal) on at least one mature B-cell- (cluster 2) and one plasma cell-like (cluster 10) LPL tumor subpopulation after vaccination, CellChat analysis predicted overall decreased signaling to SIRPα on myeloid cells which expression was confirmed on classical monocytes (Fig. 4E). The gene discussed is LPL; the disease is neoplasm.