To further explore the complex heterogeneity of this disease, we compared our RNA-seq data to a set previously published by Roberts, et al.44 We intersected significant (P < 0.01) DEGs between the two studies that allowed us to determine overlap between the 15 Ph-like ALL patients from Roberts, et al. with our Ph-like ALL cases as well as the ALL cases with no CRLF2 rearrangements. The gene discussed is CRLF2; the disease is acute lymphoblastic leukemia.