In this treatment, serumCystatin C and CRP were significantly reduced, and inthe statistics of the above two groups of data, thetreatment group was decreased more significantlythan the control group, and the BDNF was increasedsignificantly, relative to the control group, whichshowing that pramipexole plays a very good role inregulating the serum content of PD. The gene discussed is CRP; the disease is Parkinson disease.