Ferritin rises in PCOS patients, especially withabnormal sugar levels, due to high iron in the blood,this high iron is associated with several factors such asmenstrual disorders, insulin resistance, and low hepcidinthat increases iron absorption, it is not likely thatelevated androgens may improve erythropoiesis dueto transferrin level do not rise in PCOS women[6].The decreased hepcidin was observed in femalepatients and it showed a clear association with insulinresistance which may work together to increase therisk of PCOS [7]. The gene discussed is HAMP; the disease is polycystic ovary syndrome.