The current study recorded a significantdecrease in the concentration of serum hepcidin,transferrin and estradiol, while data showed a significantincrease in the concentration of ferritin, iron,progesterone and testosterone, but prolactin didn’tshown a significant difference in PCOS patients comparedwith control group, as showed in the Table 1. This evidence concerns the gene HAMP and polycystic ovary syndrome.