A significant decrease in the level of serum hepcidinwas observed in PCOS women with hirsutismand a significant decrease in hepcidin was observedin PCOS women with oligoamenorrhea, while a significantincrease in hepcidin was observed in PCOSpatients with menorrhagia, also non-significant variance was recorded in the serum hepcidin accordingto BMI, age, and infertility issues in PCOS patientscompared, Table 3. This evidence concerns the gene HAMP and polycystic ovary syndrome.