CD4 and neoplasm: Tumor = 0.64 ± 0.15 (p < 0.05 vs. model group) T cell (CD3+) = 55 ± 8.3 (%) PD-1 T cell = 20.83 ± 6.25 (%) Tim-3 T cell = 22.5 ± 9.1 (%) (p < 0.05) Tc cell CD3+CD8+ = 27.6 ± 7 (%) (p < 0.01) Th cell CD3+CD4+ = 10.67 ± 1.95 (%) (p < 0.05) Chao1 index = 1885.71 ± 380.29 (p < 0.05) ACE index = 1866.6 ± 380.4 (p < 0.05)