Tumor = 0.52 ± 0.12 (p < 0.05 vs. model group) T cell (CD3+) = 47.5 ± 9.1 (%) PD-1 T cell = 14.9 ± 5.1 (%) Tim-3 T cell = 14.9 ± 6.7 (%) (p < 0.01) Tc cell CD3+CD8+ = 21.03 ± 7.01 (%) (p < 0.01) Th cell CD3+CD4+ = 9.9 ± 2.13 (%) Chao1 index = 1809.52 ± 190.48 (p < 0.05) ACE index = 1733.3 ± 361.7 (p < 0.05). This evidence concerns the gene CD4 and neoplasm.