PD-1 mRNA relative fold of change in tumor = 1.42 ± 0.26 PD-1 μg/mg protein = 3.33 ± 0.33 CTLA-4 mRNA relative fold of change in tumor = 1.37 ± 0.29 CTLA-4 IOD/106 pixel in tumor = 666 ± 166. The gene discussed is RPL17; the disease is neoplasm.