revealed that good gut microbiota could improve tumor responsiveness to anti‐programmed death 1 (PD‐1) and its ligand 1 (PD‐L1) by suppressing the PD‐L2 ‐repulsive guidance molecule b (RGMb) pathway between dendritic cells (DCs) and T cells in different mouse models.1 The gene discussed is PDCD1LG2; the disease is neoplasm.