When separated patients into high/median/low‐expression group of PD‐L1+CD8+T cell or CTLA4+CD8+T cell based on the combination of PD‐L1/CD8A or CTLA4/CD8A mRNA expression level (e.g., high expression of both PD‐L1 and CD8A represented as “high” group), such two immunosuppressive cells were also more abundant in SCLC‐V subtype (Figure S4E), which was concordant with the fluorescence results. This evidence concerns the gene CD8A and small cell lung carcinoma.