Although the positive impact on associated pathologies was not officially registered in the database, the favorable acupuncture–hypertension and acupuncture–diabetes interactions that were observed (data not shown) are well supported by other studies.31, , –34 Taken together, this supports the need for a prospective study comparing the present approach with an accepted standard treatment like an oral glucagon-like peptide (GLP)-1 analogue. The gene discussed is GCG; the disease is diabetes mellitus.