Moreover, Western blot analysis also showed that the expression of hepatic stellate cell activation markers (α‐SMA, fibronectin, and COL1A1) decreased after co‐culture with KD‐cPKM ICC cells and increased after co‐culture with OE‐cPKM ICC cells (Figure 2G). Here, FN1 is linked to intrahepatic cholangiocarcinoma.