We also performed MR analysis for other interleukin factors and found that only IL-14 had a significant causal effect on the increased risk of IPF (random-effect model IVW: OR, 1.001; 95% CI, 1.000-1.001, P = 0.026) (Table 1). The gene discussed is TXLNA; the disease is idiopathic pulmonary fibrosis.