We also found that 9 functional-validated Aβ phagocytic AD MG DEGs, out of 130, were shared in both humans/mice and functional Aβ phagocytosis model (CHST11, DPP7, LPAR6, LPL, P2RY12, PLD1, SERPINF1, SPP1, TMEM163). The gene discussed is SPP1; the disease is Alzheimer disease.