NDUFS7 and amyotrophic lateral sclerosis: Other DEGs affected by the identified candidate SNPs included NDUFS7, a mitochondrial respiratory complex component associated with several neurological disorders [69], PTBP1, a regulator of neuronal pre-mRNA splicing associated with frontotemporal dementia and amyotrophic lateral sclerosis [70, 71], and SC5D, a cholesterol biosynthesis enzyme associated with lathosterolosis, a congenital disorder affecting central nervous system development [72], all in Oligo4, and RPS15 [61] in Oligo6 (Additional file 2: Table S13).