In Micro1, DEGs affected by the catalogued candidate regulatory SNPs included MYO1E, an actin-based molecular motor protein previously found to be differentially expressed in a microglial model of AD [63, 64] (Fig. 7c, Additional file 1: Figure S7c-f, Additional file 2: Tables S13 and S14) and APOE [14, 15] (Fig. 7d, Additional file 1: Figure S7g–i, Additional file 2: Tables S13 and S14). Here, APOE is linked to Alzheimer disease.