Immunohistochemically, the tumor cells showed strong pancytoplasmic staining of the type III receptor tyrosine kinase (KIT) (Fig. 5D) and the transmembrane protein discovered on GIST (DOG1) (Fig. 5E) [9] and negative staining for S100 (Fig. 5F) and desmin (Fig. 5G). Here, DES is linked to neoplasm.