Age (p < 0.001), osteoporosis (p < 0.001), TC (p = 0.007), LDL (p = 0.019), lumbar CT value (p < 0.001) and Hcy (p = 0.001), SOD (p < 0.001), GR (p = 0.015), and fusion rate (p = 0.007) were statistically significant between high score group (cumulative grade > 18) and low score group (cumulative grade ≤ 18). The gene discussed is GSR; the disease is osteoporosis.