We predicted UNC5A would be involved, based on (i) its role in mediating apoptosis29,36,37; (ii) the exceptionally strong miR-214-3p binding site of the 3’ untranslated region (UTR) of UNC5A, consisting of 13 consecutive base pairings from the 5’-end of the miRNA; and (iii) the UNC5A ligand, netrin-1 (NTN1) gene being a proven target of miR-214-3p in bladder cancer cells38. Here, UNC5A is linked to urinary bladder carcinoma.