For example, similar to previous bioinformatics studies of endometriosis, we found that ECM-receptor interactions, cytokine–cytokine receptor interactions, immune–stromal cell interactions, coagulation cascades, and TGF-β signaling were dysregulated in endometriosis tissue compared to healthy endometrium [7, 43–46]. This evidence concerns the gene TGFB1 and endometriosis.