SLC4A11 and Fuchs endothelial corneal dystrophy: Given the uncertain influence of microelement borate homeostasis on the human body, apparent changes in pHi and osmotic pressure are more likely to underlie SLC4A11-mutation associated diseases such as congenital hereditary endothelial dystrophy (CHED)10–12, Fuchs’ endothelial corneal dystrophy (FECD)13 and Harboyan syndrome (or corneal dystrophy and perceptive deafness, CDPD)14.