INS and cardiovascular disorder: Studies in the general population have reported that for every 30 minutes of sedentary behavior reallocated to light-intensity or moderate to vigorous intensity physical activity, there is a 2% to 25% improvement in cardiovascular disease risk biomarkers [63], and a 1- to 2-hour reduction in television viewing time is associated with reductions in cardiovascular disease risk (eg, waist circumference, BMI, triglycerides, insulin sensitivity, and blood pressure) [64,65].