For instance, the anti-EGFR antibody cetuximabwas conjugated to the NIR fluorophore IRDye800CW and used in 12 patientsundergoing surgical resection of SCC arising in the head and neck(NCT01987375).52 Fluorescence intraoperativewide-field imaging was employed to differentiate between tumor andnormal tissues with average tumor-to-background ratios over 5. The gene discussed is EGFR; the disease is neoplasm.