S100A8 and COVID-19: In contrast to published studies,we did not observe significantserum S100A8/A9 variation related to length of hospitalization orventilation requirement.11,24,39 However, this lack of variation may be advantageous, as routinebiomarkers such as CRP and procalcitonin may be influenced by potentialconcomitant bacterial co-infection.24 Theseconclusions are supported by previous studies that observed elevatedS100A8/A9 levels in severe COVID-19 patients occurring irrespectiveof concomitant bacterial co-infections.9