On the other hand, tumor‐associated neutrophil has been proven to be induced by the immunosuppressive cytokine transforming growth factor‐beta (TGF‐β) in the cancer setting to acquire a protumorigenic (N2) phenotype, playing a role in tumor growth, invasion, angiogenesis, and immunosuppression.34, 35. The gene discussed is TGFB1; the disease is cancer.