Small‐molecule modulators of aerobic glycolysis (e.g. dichloroacetate), and Shh and Notch signaling pathways (e.g. vismodegib and DAPT, respectively), that are widely tried as potent anti‐cancer agents, have also been shown to possess strong anti‐platelet/anti‐thrombotic attributes [4, 5]. The gene discussed is SHH; the disease is cancer.