Transferrin saturation has been found to be less affected than serum ferritin by inflammation and malaria parasitaemia when tested against other iron markers26 (including iron, transferrin levels, hepcidin, haemoglobin, and serum transferrin receptor) and was found to most closely match the current gold standard for iron deficiency measurement (regression corrected ferritin levels). This evidence concerns the gene HAMP and Iron deficiency anemia.