GM is primarily influenced by Omega‐3 under the following circumstances: (1) Omega‐3 influences the composition of GM; (2) Omega‐3 affects GM metabolic substances, such as proinflammatory mediators, that is, endotoxins (lipopolysaccharides) and IL‐17; (3) Omega‐3 regulates the levels of SCFAs, but its rationale for treating AD is not clear, so we can only assume that it may be used to treat AD based on the following available findings.66 The gene discussed is IL17A; the disease is Alzheimer disease.