SLC25A27 and Parkinson disease: By knocking out DJ‐1, which is one of the genes related to early‐onset forms of PD and the expressions of two uncoupling proteins UCP4 (SLC25A27) and UCP5 (SLC25A14) were downregulated, calcium‐induced uncoupling and increment of oxidation of matrix proteins were compromised powerfully in the substantia nigra pars compacta (SNc) dopaminergic neurons.