In a word, previous studies mainly concentrated on the roles of SAMSN1 in varieties of cancers such as gastric cancer,7 multiple myelomas (MM),9 colorectal cancer,10 hepatocellular carcinomas,11 and angioimmunoblastic T‐cell lymphoma,12 which indicated that SAMSN1 is closely associated with cancer and immune system disease. The gene discussed is SAMSN1; the disease is colorectal cancer.