These data showed SFXN4 expression were consistently upregulated in all the six GEO datasets (Figure 2A-F); the expression of SFXN1 and SFXN5 in HCC tissues decreased in three datasets, while remained unchanged in the other three datasets; the expression of SFXN2 decreased in four datasets, increased in one dataset, and remained unchanged in one dataset; the expression of SFXN3 decreased in one dataset, and remained unchanged in five datasets (Table 1). This evidence concerns the gene SFXN1 and hepatocellular carcinoma.