SFXN4 and hepatocellular carcinoma: Analysis of TCGA-GTEx database showed that, in normal and HCC, the expression levels of SFXN1 (4.543 ± 0.509 vs. 4.499 ± 0.826, P > 0.05) and SFXN2 (3.21 ± 0.58 vs. 3.123 ± 0.912, P > 0.05) were not dramatically changed, while SFXN3 (2.136 ± 0.805 vs. 2.394 ± 1.019, P < 0.01) and SFXN4 (4.15 ± 0.479 vs. 4.854 ± 0.636, P < 0.001) were dramatically upregulated in HCC samples, however, SFXN5 expression (4.5 ± 0.644 vs. 4.043 ± 0.739, P < 0.001) was decreased in HCC tissues (Figure 1A, Figure S1).