ARF1 and neoplasm: A recent study reported that endogenous damage‐associated molecular patterns (DAMPs), such as reactive oxygen species (ROS) and oxidized lipids, could activate inflammasome in the tumor‐infiltrating DCs.[38] Arf1 had a critical role in mediating lipolysis and its ablation resulted in ROS increase and lipid droplet accumulation.[27, 28] The elevated ROS may further promote lipid oxidation.