ELK4 was also found to be a tumor suppressor gene that suppresses the proliferation and promotes the apoptosis of vestibular schwannoma cells.[9] Previously, we revealed the protumorigenic role of LAMB3 in CRC and showed that transcriptional upregulation of LAMB3 is regulated by ELK4, suggesting the potential oncogenic role of ELK4 in CRC.[10] However, the biological function and regulatory mechanism of ELK4 in CRC remain unknown. This evidence concerns the gene ELK4 and colorectal carcinoma.