Integrins (ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA8, ITGAV, ITGAX, ITGAM, ITGB1 and ITGB2) expressed in tumours have the ability to identify various ligands such as collagens, FN1 and LAMININ. The gene discussed is ITGB1; the disease is neoplasm.