Beside the inverse association with global antemortem cognitive scores of participants (r2 = -0.09, P < 0.05, Figs. 1D and 3), higher postmortem TBS-soluble concentrations of ACE2 were also significantly correlated with failing episodic memory, a domain predominantly affected in AD (Fig. 3). The gene discussed is ACE2; the disease is Alzheimer disease.