Our analysis of signaling pathways contributing to regulation of LINC00707 expression (Fig. 3) have also indicated subtle differences between normal or cancer cell models of different tissue origin, as is the case of the contribution of JNK, MEK and p38 MAPK in HaCaT, PC3U and GBM cells (Fig. 3C). The gene discussed is MAP2K7; the disease is glioblastoma.